Advanced Functional Materials and Nanotechnology for Medicine, Environment and Energy are topics for doing fundamental and application-oriented research projects at the NEB research group. Advanced nanostructures and nanotechnological engineering are key factors for producing new innovations & international recognized quality. The NEB research group is focusing on advanced nanomaterials, nanohybrids, nanocomposites and their applications to energy and biomedical industry.
Research at NEB is based on interdisciplinary approach by covering advanced materials science, nanoscience and nanotechnology for improving technological innovation and product quality. The researchers at NEB consist of domestic research scientists and collaborators with expertise in the different field, our manpower will maintain our position as one of the leading research group in the field of nano energy and nano-biomedical.
Core values at NEB are Creativity + Passion and Trust + Harmony
Synthesis, characterizations of superparamagnetic Fe3O4-Ag hybrid nanoparticles and their application for highly effective bacteria inactivation
Le Minh Tung, Nguyen Xuan Cong, Le Thanh Huy, Nguyen Thi Lan, Vu Ngoc Phan, Nguyen Quang Hoa, Le Khanh Vinh, Nguyen Viet Thinh, Le Thanh Tai, Duc-The Ngo, Kristian Mølhave, Tran Quang Huy, Anh-Tuan Le
In recent years, outbreaks of infectious diseases caused by pathogenic micro-organisms pose a serious threat to public health. In this work, Fe3O4-Ag hybrid nanoparticles were synthesized by simple chemistry method and these prepared nanoparticles were used to investigate their antibacterial properties and mechanism against methicilline-resistant Staphylococcus aureus (MRSA) pathogen. The formation of dimer-like nanostructure of Fe3O4-Ag hybrid NPs was confirmed by X-ray diffraction and High-resolution Transmission Electron Microscopy. Our biological analysis revealed that the Fe3O4-Ag hybrid NPs showed more noticeable bactericidal activity than that of plain Fe3O4 NPs and Ag-NPs. We suggest that the enhancement in bactericidal activity of Fe3O4-Ag hybrid NPs might be likely from main factors such as: (i) enhanced surface area property of hybrid nanoparticles; (ii) the high catalytic activity of Ag-NPs with good dispersion and aggregation stability due to the iron oxide magnetic carrier, and (iii) large direct physical contacts between the bacterial cell membrane and the hybrid nanoparticles. The superparamagnetic hybrid nanoparticles of iron oxide magnetic nanoparticles decorated with silver nanoparticles can be a potential candidate to effectively treat infectious MRSA pathogen with recyclable capability, targeted bactericidal delivery and minimum release into environment.
In recent years a growing number of outbreak of infectious diseases has emerged over the world.The outbreak of re-emerging and emerging infectious diseases is a considerable burden on global economies and public health. Nano-antimicrobials have been studied as an effective solution for the prevention of infectious diseases. In this work, we demonstrated a modified photochemical approach for preparation of carbon nanotubes-silver nanoparticles (CNTs-Ag) and graphene oxide-silver nanoparticles (GO-Ag) nanocomposites, which can be stably dispersible in aqueous solution. The formation of silver nanoparticles (Ag-NPs) on the functionalized CNTs and GO nanosheets was analyzed by X-ray diffraction, transmission electron microscopy, Raman spectroscopy and UV-vis measurements. These analyses indicated that the average particle sizes of Ag-NPs deposited on GO/CNTs nanostructures were approximately ~6-7 nm with nearly uniform size distribution. Moreover, these nanocomposites were found to exhibit enhanced antibacterial activity against two strains of infectious bacteria including Gram-negative Escherichia Coli and Gram-positiveStaphylococcus aureusbacteria as compared to bare Ag-NPs. Our obtained studies showed a high potential of GO-Ag and CNTs-Ag nanocomposites as effective and long-term disinfection solution to eliminate infectious bacterial pathogens.